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Vitamin B7/biotin Feed Grade
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Properties
Product Name Vitamin B7/Biotin Feed Grade
CAS Number 58-85-5
Formula C10H16N2O3S
Molar Mass 244.31 g/mol
Pub Chem CID 171548
Drug Bank DB00121
Chem Spider 1490
Bioavailability High
Protein Binding 80%
Metabolism Hepatic
Elimination Halflife 26 hours
FAQ
What is Vitamin B7/Biotin Feed Grade and why is it important for animal nutrition?

Vitamin B7, commonly known as Biotin, is an essential water-soluble vitamin that plays a critical role in animal metabolism. It is a coenzyme in various biochemical reactions that involve the metabolism of lipids, carbohydrates, and proteins. For animals, particularly livestock such as poultry, swine, and ruminants, adequate biotin levels are indispensable for optimal growth, reproduction, and maintenance of general health.

Biotin is crucial for several key physiological functions, including the synthesis of fatty acids, the catabolism of amino acids, and the generation of glucose from non-carbohydrate sources. Without sufficient biotin, animals may experience issues such as impaired growth, poor feathering or coat quality, and reproductive inefficiencies. Additionally, biotin deficiency can result in cracked hooves, skin lesions, and diminished feed efficiency. Ensuring an adequate supply of Biotin Feed Grade in the diet helps prevent these issues and supports overall animal well-being.

How does Biotin Feed Grade work to improve hoof and skin health in livestock?

Biotin Feed Grade significantly contributes to hoof and skin health by acting as a coenzyme that catalyzes important biochemical reactions essential for maintaining cellular integrity. For hooves, biotin plays a crucial role in the synthesis of keratin—a structural protein that forms the hoof's outer layer. Adequate biotin levels contribute to stronger, more resilient hooves, reducing the risk of conditions such as hoof cracks and ulcers. This is particularly important for dairy and beef cattle, pigs, and horses, where hoof health directly affects mobility and, consequently, productivity.

In terms of skin health, biotin aids in the maintenance of fatty acid metabolism, ensuring the production of oils that keep the skin supple and hydrated. Animals with a biotin deficiency often exhibit signs of dermatitis, alopecia, and other skin conditions. By incorporating Biotin Feed Grade in the diet, lipid metabolism is optimized, leading to healthier skin and an improved external appearance. This is especially beneficial for poultry, where feather development and quality are directly influenced by biotin availability, resulting in better protection against environmental stresses and parasites.

What are the symptoms of biotin deficiency in animals, and how can they be addressed?

Biotin deficiency in animals can manifest in several noticeable and detrimental ways. Common symptoms include poor growth rates, dull and thinning coats or plumage, dermatitis, and cracked hooves. In severe cases, reproductive inefficiencies and neurological issues may also arise. For poultry, symptoms often include poor feathering, dermatitis, and fatty liver syndrome. Swine may display signs such as footpad cracking, alopecia, and decreased reproductive performance. Ruminants and horses with biotin deficiency often suffer from brittle hooves and skin lesions.

Addressing biotin deficiency involves dietary supplementation with Biotin Feed Grade. The appropriate dose depends on the species, age, and physiological state of the animal. Preventative and corrective measures typically involve ensuring that the animal's diet contains the recommended daily intake of biotin, which varies for different livestock. Immediate intervention might be necessary for severely deficient animals, often through direct supplementation and improvements in overall dietary quality. Long-term strategies include working with a nutritionist or veterinarian to formulate and maintain nutritionally balanced rations that include adequate levels of biotin.

How is Biotin Feed Grade metabolized and utilized in animal bodies?

Upon ingestion, Biotin Feed Grade is absorbed in the small intestine, primarily via a specialized carrier-mediated transport system. Once absorbed, biotin enters the bloodstream and is distributed to various tissues where it is required. Biotin functions as a coenzyme for carboxylases, crucial enzymes involved in critical metabolic pathways. These pathways include gluconeogenesis, fatty acid synthesis, and the catabolism of branched-chain amino acids.

In the liver, biotin is incorporated into carboxylase enzymes that assist in synthesizing glucose from non-carbohydrate sources, a vital process during periods of low carbohydrate availability. In adipose tissue, biotin-dependent carboxylases are essential for fatty acid synthesis, ensuring that lipid reserves are maintained. Similarly, in muscle tissue, biotin helps in the metabolism of amino acids, which are crucial for maintaining muscle integrity and function.

Biotin is also essential for maintaining cell signaling and gene regulation processes. It influences the expression of genes involved in the metabolism and overall physiological functions. Thus, by ensuring adequate biotin levels through feed supplementation, animals can maintain optimal metabolic functions necessary for growth, reproduction, and general health.

What factors can influence the biotin requirements of animals?

Several factors can influence the biotin requirements of animals, including species, age, physiological state, environmental conditions, and overall diet composition. Different species have variable requirements for biotin due to differences in metabolic rates and physiological needs. For example, poultry generally has higher biotin requirements than ruminants due to their faster growth rates and feather production needs.

Age is another significant factor; young, growing animals tend to have higher biotin needs compared to mature or maintenance-phase animals. Reproductive status also plays a role; lactating or pregnant animals require more biotin to support fetal development and milk production.

Environmental stressors like extreme temperatures, poor housing conditions, or high disease pressure can increase biotin requirements as the animal's metabolic demands rise to cope with stress. Furthermore, the overall diet composition, including the availability of other vitamins and minerals, affects biotin utilization and needs. Diets high in antagonists like raw egg whites, which contain avidin, can inhibit biotin absorption, thereby increasing the dietary requirement for biotin.

How can Biotin Feed Grade supplementation enhance feed efficiency and production performance in livestock?

Biotin Feed Grade supplementation can greatly enhance feed efficiency and production performance by optimizing metabolic processes. As a crucial coenzyme in several metabolic pathways, biotin ensures efficient utilization of feed nutrients. For instance, improved fatty acid and glucose metabolism lead to better energy utilization, enabling animals to convert feed into body mass and production outputs more efficiently.

Poultry supplemented with biotin exhibit better feathering, improved feed conversion ratios, and higher egg production rates. In swine, biotin improves reproductive performance and litter quality, enhancing overall production efficiency. For ruminants, enhanced hoof health due to biotin supplementation translates into better mobility, increased grazing, and, consequently, higher milk yields in dairy cattle and better weight gains in beef cattle. Horses experience improved hoof integrity, leading to more consistent performance, especially in working and competitive animals.

Supplementing with Biotin Feed Grade not only addresses deficiency symptoms but also promotes an optimized metabolic state, ensuring that animals perform at their peak. This leads to better overall production metrics, such as growth rates, reproductive efficiency, and product quality.
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