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Tetramisole Hydrochloride Feed Grade
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Properties
Product Name Tetramisole Hydrochloride Feed Grade
CAS Number 5086-74-8
Formula C11H13ClN2S
Molar Mass 240.75 g/mol
Pub Chem CID 27221
Drug Bank DB11447
Chem Spider 25351
Bioavailability High
Protein Binding 30-46%
Metabolism Hepatic
Elimination Halflife 4-6 hours
FAQ
What is Tetramisole Hydrochloride Feed Grade and how does it benefit the feed industry?
Tetramisole Hydrochloride Feed Grade is an anthelmintic agent specifically formulated to be included in animal feed to combat parasitic worms, particularly in livestock and poultry. Its primary benefit lies in its efficacy in deworming animals, which enhances their overall health and productivity. Parasitic worms are notorious for causing a range of issues, from reduced growth rates to lowered immunity, which can lead to secondary infections. By incorporating Tetramisole Hydrochloride into feed, producers can ensure their livestock remain free from these parasites, leading to better feed conversion rates and ultimately, higher yield and profitability.

The feed-grade formulation of Tetramisole Hydrochloride also ensures its compatibility with other feed components, maintaining the nutritional integrity of the feed. It is designed to be easy to incorporate, either by mixing directly into the feed or through pre-blended premixes. This offers a practical and efficient solution for large-scale operations, saving time and reducing labor costs associated with individual animal treatments.

What are the main parasitic worms targeted by Tetramisole Hydrochloride in livestock and poultry?
Tetramisole Hydrochloride is particularly effective against a variety of gastrointestinal nematodes, which are common troublemakers in the livestock and poultry industries. These nematodes include species such as Haemonchus, Ostertagia, Trichostrongylus, and Cooperia in ruminants, as well as Ascaridia, Heterakis, and Capillaria in poultry. These parasites can cause significant health issues, including anemia, reduced milk production, diarrhea, and overall poor body condition, which ultimately affect the productivity and profitability of livestock and poultry operations.

By targeting these specific parasites, Tetramisole Hydrochloride ensures a broad spectrum of action, making it an invaluable tool in maintaining the health of animals across various types of farming setups. Eliminating these worms helps improve nutrient absorption, as infested animals often suffer from malnutrition despite having adequate feed. This not only leads to better growth rates and weight gain but also enhances the welfare of the animals.

What is the recommended dosage of Tetramisole Hydrochloride Feed Grade for different types of animals?
The recommended dosage of Tetramisole Hydrochloride Feed Grade can vary depending on the species of animal and the level of infestation. For cattle, sheep, and goats, a typical dosage might range from 7.5 to 10 mg per kilogram of body weight administered orally. For poultry, the dosage often lies around 40-50 mg per kilogram of feed. However, precise dosages can depend on specific factors such as the severity of the infestation, the age and size of the animals, and the specific farm management practices.

It is crucial to follow veterinary guidelines and manufacturer’s instructions to ensure that the dosage is accurate and effective. Overdosage can lead to toxicity, while underdosing can result in ineffective treatment and possible resistance development in parasites. Regular monitoring and consultation with a veterinary professional are recommended to tailor the dosage to the particular needs of the livestock or poultry.

How is Tetramisole Hydrochloride Feed Grade administered in animal feed?
Tetramisole Hydrochloride Feed Grade can be administered through two main methods: direct mixing into the feed or through premixes. When directly mixing, it is important to ensure that the Tetramisole Hydrochloride is evenly distributed throughout the feed, which might require the use of mechanical mixers, particularly in large-scale operations. This ensures that each animal receives the appropriate dose with their daily feed intake.

Premixing involves blending the Tetramisole Hydrochloride with a smaller portion of feed before incorporating it into the larger batch. This method can be especially useful in ensuring uniform distribution and making the handling of the product more manageable. Both methods are designed to be efficient and to minimize the labor involved in administering the anthelmintic treatment, making it a practical solution for large farms.

In either method, it’s essential to follow proper protocols and guidelines to avoid contamination and ensure the safety and efficacy of the product. Regular training and adherence to manufacturer’s instructions can help in achieving the best results.

What are the safety precautions when using Tetramisole Hydrochloride Feed Grade?
Safety is paramount when using any pharmaceutical product, and Tetramisole Hydrochloride Feed Grade is no exception. It is important to store the product in a cool, dry place away from direct sunlight and moisture, as these factors can degrade the active ingredients. Always keep it out of reach of children and unauthorized personnel to prevent accidental ingestion or misuse.

While Tetramisole Hydrochloride is generally safe when used according to guidelines, it is essential to follow dosage instructions carefully to avoid overdosage, which can lead to toxicity. Symptoms of toxicity might include muscle tremors, hyperexcitability, or salivation. If such symptoms occur, remove the feed containing Tetramisole and consult a veterinarian immediately.

Handlers should use personal protective equipment (PPE), such as gloves and masks, to avoid direct contact with the product, as prolonged exposure can lead to skin irritation or respiratory issues. It is also advisable to wash hands thoroughly after handling to prevent any accidental ingestion.

What is the impact of Tetramisole Hydrochloride on animal growth and productivity?
The impact of Tetramisole Hydrochloride Feed Grade on animal growth and productivity is highly positive, especially in environments where parasitic worm infestations are prevalent. By effectively eliminating a range of parasitic worms, Tetramisole Hydrochloride helps to improve the overall health of the animals, which directly correlates with better growth rates and higher productivity.

Infested animals often show signs of poor growth, weight loss, and decreased milk or egg production. They may also suffer from secondary infections due to a weakened immune system. By eradicating the parasites, Tetramisole Hydrochloride ensures that animals can absorb nutrients more efficiently, leading to better feed conversion rates. This means that animals gain weight and grow faster on the same amount of feed, making the farming operation more cost-effective.

Improved health also means reduced veterinary expenses and lower mortality rates. Healthy animals require fewer medical interventions and are less likely to succumb to diseases, leading to more predictable and stable production cycles. This stability is crucial for long-term planning and profitability in the feed industry.

How does Tetramisole Hydrochloride compare to other anthelmintic agents in terms of effectiveness and safety?
Tetramisole Hydrochloride is often compared to other anthelmintic agents due to its broad-spectrum efficacy and safety profile. One of its main advantages is its effectiveness against a variety of gastrointestinal nematodes, which makes it a versatile solution for different types of livestock and poultry. Compared to other anthelmintics, Tetramisole Hydrochloride has a quick onset of action, often leading to noticeable improvements in animal health within a short period.

In terms of safety, Tetramisole Hydrochloride has a well-established safety profile when used according to recommended dosages. It poses minimal risks of toxicity, especially when compared to some older anthelmintics that have narrower safety margins. Its compatibility with other feed components further enhances its safety, making it a reliable choice for integrated feed formulations.

However, like all anthelmintics, it is important to use Tetramisole Hydrochloride as part of a comprehensive parasite control program, which might include rotational use of different classes of anthelmintics to prevent resistance development. Regular monitoring and diagnostic testing can help in managing the long-term effectiveness and safety of Tetramisole Hydrochloride in any feed operation.
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